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Eberly HallPittsburgh, PA 15260
Research Overview
The human body emits a complex blend of hundreds of volatile organic compounds (VOCs), collectively known as the volatilome, through exhaled breath, skin, and bodily fluids. Influenced by factors such as disease, nutrition, environment, and the microbiome, the chemical study of the volatilome can provide unparalleled insight into human health and physiology.
The Rankin-Turner lab uses ambient ionization mass spectrometry and gas chromatography/mass spectrometry to study the human volatilome. Employing comprehensive profiling of whole body, skin, and exhaled breath volatiles, our research aims to elucidate how the chemistry of the human body changes in response to factors such as disease, infection and the environment. We can then leverage this information to develop new tools for the study and non-invasive diagnosis of diverse health conditions, bridging the gap between laboratory research and clinical practice. Our research incorporates aspects of analytical chemistry, clinical chemistry, biochemistry, and data science. Members of the Rankin-Turner lab gain expertise in mass spectrometry, separation science, use and modification of analytical instrumentation, analysis of complex datasets, and managing human subjects research.